产品货号：
GS4747
中文名称：
重组人Bcl-xL
英文名称：
Recombinant Human B-cell lymphoma-extra large
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 23.7kDa,a single non-glycosylated polypeptide chain containing 211 amino acids.
储存条件：冷冻（-20℃）
概述
Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic,such as adult brain cells.It plays a role in the signal transduction pathway of the FAS-Ligand.Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers,and this is an significant event in the regulation of apoptosis.It is involved in the survival of cancer cells.Bcl-xL is the leading monitor of apoptosis/active cell suicide.It has cell death repressor activity and therefore acts as a survival protein.The human Bcl-xL shares 97%a.a.sequence identity with murine and rat Bcl-xL.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人Bcl-xL，Bcl-xL, Human，Recombinant Human B-cell lymphoma-extra large
储存条件：冷冻（-20℃）
概述
Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic,such as adult brain cells.It plays a role in the signal transduction pathway of the FAS-Ligand.Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers,and this is an significant event in the regulation of apoptosis.It is involved in the survival of cancer cells.Bcl-xL is the leading monitor of apoptosis/active cell suicide.It has cell death repressor activity and therefore acts as a survival protein.The human Bcl-xL shares 97%a.a.sequence identity with murine and rat Bcl-xL.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Test in Process. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris-HCl,pH 8.0,5%Trehalose. |
| 内毒素 | Less than 0.1 EU/μg of rHuBcl-xL as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEGT ESEMETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIAAWMA TYLNDHLEPW IQENGGWDTF VELYGNNAAA ESRKGQERFN R |
相关搜索：重组人Bcl-xL，Bcl-xL, Human，Recombinant Human B-cell lymphoma-extra large